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Medical device manufacturer

Ortho-Clinical Diagnostics, Inc.

Ortho-Clinical Diagnostics, Inc. holds 142 FDA 510(k) clearances across 77 product codes. Median elapsed review time is 57 days. openFDA lists 354 recall records naming the company. FDA publishes it under 21 different spellings, all counted here as one company.

Updated · ingest status · JSON

510(k) clearances
142
Product codes
77
Median review
57 days
Recall records
354

How does FDA spell Ortho-Clinical Diagnostics, Inc.?

FDA publishes this company under 21 different spellings across its datasets. Every figure on this page counts all of them as one company, which is why the totals here are higher than a search for any single spelling would give you.

Every spelling FDA published for this company, and which dataset each came from.
As FDA published itDatasetMatched by
ORTHO-CLINICAL DIAGNOSTICSdevice/recallnormalised
ORTHO-CLINICAL DIAGNOSTICSdevice/enforcementnormalised
ORTHO-CLINICAL DIAGNOSTICS, INC.device/registrationlistingnormalised
Ortho Clinical Diagnosticsdevice/enforcementnormalised
Ortho Clinical Diagnosticsdevice/recallnormalised
Ortho Clinical Diagnosticsdevice/registrationlistingnormalised
Ortho Clinical Diagnosticsdevice/510knormalised
Ortho Clinical Diagnostics Incdevice/recallnormalised

Showing 8 of 21.

Merges are measured against a hand-labelled sample and held above 98% precision. Pairs the matcher is unsure of are queued for a person rather than merged, because two genuinely different firms with similar names is the error that would corrupt every count on this page.

Which product codes does Ortho-Clinical Diagnostics, Inc. file in?

77 product codes, ranked by how much they file in each.

Product codes this company holds clearances in, with their median elapsed review time in each.
CodeDeviceClearancesMedian reviewLatest
JJXSingle (Specified) Analyte Controls (Assayed And Unassayed)1328 days
MMIImmunoassay Method, Troponin Subunit685 days
JFYEnzymatic Method, Creatinine523 days
JJYMulti-Analyte Controls, All Kinds (Assayed)528 days
JITCalibrator, Secondary445 days
JIXCalibrator, Multi-Analyte Mixture418 days
CGZElectrode, Ion-Specific, Chloride390 days
DCKC-Reactive Protein, Antigen, Antiserum, And Control328 days
DHXSystem, Test, Carcinoembryonic Antigen371 days
JISCalibrator, Primary319 days
KHSEnzymatic, Carbon-Dioxide3143 days
CDDRadioassay, Vitamin B12250 days
CDNUrease, Photometric, Urea Nitrogen229 days
CEMElectrode, Ion Specific, Potassium229 days
CEWRadioimmunoassay, Parathyroid Hormone2105 days
CGAGlucose Oxidase, Glucose230 days
CGNAcid, Folic, Radioimmunoassay212 days
CGRRadioimmunoassay, Cortisol250 days
CIXBromcresol Green Dye-Binding, Albumin219 days
CJYAzo Dye, Calcium221 days
DHASystem, Test, Human Chorionic Gonadotropin2115 days
DLZEnzyme Immunoassay, Phenobarbital256 days
JGSElectrode, Ion Specific, Sodium241 days
JHXFluorometric Method, Cpk Or Isoenzymes221 days
JLWRadioimmunoassay, Thyroid-Stimulating Hormone256 days

Showing the 25 they file in most, of 77.

Median review is elapsed calendar days between date received and decision date, as published by FDA. It is not FDA review days — the two differ whenever the agency stops the clock for an additional information request.

Source: openFDA device/510k · retrieved

Has Ortho-Clinical Diagnostics, Inc. had a recall?

openFDA lists 354 recall records naming this company across its whole history. A recall record covers one firm's corrective action and may span many device lots.

  • Z-2559-2025Class IIOpen, ClassifiedKHP

    VITROS Chemistry Products LAC Slides on VITROS XT 3400 and VITROS XT 7600 Systems are experiencing an increased occurrence of calibration failure related to lots from coating 0130 and above with Condition Code TH4-63J during calibration, causing the delay of lac test results and potentially impact patient management. The issue was identified by QuidelOrtho through an increase in customer complaints compared to the historical baseline with average failure rate of 1% for coating 0130 in 2025 while average of failure rate for other coating was 0.06% in 2025 and average of failure rate for all coatings is 0.03% for 2024.

  • Z-2560-2025Class IIOpen, ClassifiedKHP

    VITROS Chemistry Products LAC Slides on VITROS XT 3400 and VITROS XT 7600 Systems are experiencing an increased occurrence of calibration failure related to lots from coating 0130 and above with Condition Code TH4-63J during calibration, causing the delay of lac test results and potentially impact patient management. The issue was identified by QuidelOrtho through an increase in customer complaints compared to the historical baseline with average failure rate of 1% for coating 0130 in 2025 while average of failure rate for other coating was 0.06% in 2025 and average of failure rate for all coatings is 0.03% for 2024.

  • Z-2335-2025Class IIOpen, ClassifiedCJY

    Generations 67 and above of VITROS Ca Slides are experiencing an increased occurrence of Condition Code TH4-63J during calibration on VITROS XT 3400 and VITROS XT 7600 Systems, causing calibration failures that delay calcium test results and potentially impact patient management. The imaging reflectometer algorithm detects excessive "spikes" (imperfections) in slide images and generates the TH4-63J condition code when the threshold of 600 spikes is exceeded. Updated analysis revealed a 19-fold increase in failure rates from 0.0043% (2024 baseline) to 0.082% for Generation 67+ slides in 2025, with 100% of calibrator failures occurring at the lowest concentration level. This can result in delayed diagnosis and treatment of conditions such as hypercalcemic crisis, parathyroid disorders, and other calcium-related emergencies requiring urgent intervention.

  • Z-2073-2025Class IIOpen, ClassifiedDJG

    Lots from Generation (GEN) 15 of VITROS Chemistry Products OP Reagent may generate lower than expected quality control (QC) results. If the customer is unable to get passing quality control results, then the customer would be unable to run the OP-LO protocol leading to a potential delay in patient results.

  • Z-2120-2025Class IIOpen, ClassifiedDIH

    Quality control (QC) drift when certain lots of Performance Verifiers (PVs) are used with certain lots of cholinesterase enzyme (CHE) slides. This drift occurs when the PVs are used 2-7 days after reconstitution; however, the label stability claims for the PV fluids is 7 days following reconstitution. This may lead to inaccurate QC results. The use of the PVs when the QC results are outside of the customer s established ranges could result in delayed results for patients due to the need to repeat QC testing or reconstitute new PV fluids and repeat testing. It could also result in erroneous patient results (small positive bias).

Showing the 5 most recently initiated of 354.

Recall class comes from openFDA's enforcement endpoint, which does not carry every recall — where it is missing, none is shown rather than guessed. Recall class I is the most serious kind of recall; device class I is the least risky kind of device, and the two are never mixed here.

Source: openFDA device/recall · retrieved

What has Ortho-Clinical Diagnostics, Inc. cleared recently?

Most recent 510(k) clearances for this company, newest first.
510(k)DeviceCodeDecisionElapsed days
K252393VITROS Immunodiagnostic Products hs Troponin I Reagent PackMMI90
K241534VITROS Immunodiagnostic Products Syphilis Reagent PackLIP90
K233581VITROS Immunodiagnostic Products Total ß-hCG II Reagent PackDHA183
K221197VITROS Immunodiagnostic Products Intact PTH II Reagent PackCEW498
K231517VITROS Immunodiagnostic Products CEA Reagent PackDHX90
K231525VITROS Immunodiagnostic Products CA 19-9TM Reagent PackNIG75
K221355VITROS Immuodiagnostic Products CA 125 II Reagent PackLTK216
K213626VITROS AFPLOJ210
K212648VITROS Immunodiagnostic Products CK-MB Reagent PackJHX158
K201312VITROS Immunodiagnostic Products NT-proBNP II Reagent PackNBC504

Source: openFDA device/510k · retrieved

Where is Ortho-Clinical Diagnostics, Inc. registered?

FDA lists 9 registered establishments for this company in US.

Registration means the firm has told FDA it makes or distributes devices from that site. It is not a clearance, an approval or an endorsement.

Watch what Ortho-Clinical Diagnostics, Inc. files next

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Data on this page comes from FDA's public openFDA API and is US public domain (CC0). DeviceSignal is an independent commercial service and is not affiliated with the U.S. Food and Drug Administration. Information only, not regulatory advice. Verify anything you rely on against open.fda.gov.