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FDA product code · Anesthesiology

BTTHumidifier, Respiratory Gas, (Direct Patient Interface)

Product code BTT covers Humidifier, Respiratory Gas, (Direct Patient Interface), a Class II device regulated under 21 CFR 868.5450. FDA has cleared 221 devices in this code, 4 of them in the last 12 months. Median review time across the 221 most recent decisions is 98 days. openFDA lists 69 recall records against this code.

Updated · ingest status · JSON

Class
Class II
Regulation
21 CFR 868.5450
Review panel
Anesthesiology
Clearances
221

What is happening in BTT right now?

BTT (Humidifier, Respiratory Gas, (Direct Patient Interface)) has two findings, most consequential first. 1 recall opened in the last 12 months and not yet terminated (Class II) (Z-0158-2026). The code is crowded, scoring 63 of 100 — 96 companies hold a clearance here and 4 arrived in the last 12 months (BTT:crowding).

Every factor behind the statement above, most consequential first, with the FDA records it came from.
FindingHow much it mattersFDA records
RecallClass II recallZ-0158-2026
CrowdingContextBTT:crowding

Sources checked: predicate ancestry, recalls, adverse events, new entrants, review time, crowding. Composed . Every finding carries the record ids it was derived from; nothing here is an estimate.

How many devices has FDA cleared in BTT?

FDA has cleared 221 devices under product code BTT since the 510(k) programme began in 1976, 4 of them in the last 12 months.

Source: openFDA device/510k · retrieved

Most recent 510(k) clearances in BTT, newest first.
510(k)DeviceApplicantDecision
K254078HVT 2.0Vapotherm, Inc.
K251448FL-10000U Respiratory HumidifierFlexicare Medical Limited.
K251419Laboratorios Biogalenic Sterile Water for Inhalation, USPLaboratorios Biogalenic S.A. DE C.V.
K253479Optiflow Switch+ Filtered Nasal Interface with CO2 Sampling (AA042J)Fisher & Paykel Healthcare, Ltd.
K250312Hudson RCI® Comfort Flo Nasal Cannula Premature, Infant; Hudson RCI® Comfort Flo Plus and Soft Plus Cannula Extra SmallMedline Industries, LP
K251611Optiflow+ Nasal Cannula - Small (OPT942); Optiflow+ Nasal Cannula - Medium (OPT944); Optiflow+ Nasal Cannula - Large (OPT946); Optiflow+ Nasal Cannula Small (MYOPT9SMALL); Optiflow+ Nasal Cannula Medium (MYOPT9MEDIUM); Optiflow+ Nasal Cannula Large (MYOPT9LARGE)Fisher & Paykel Healthcare, Ltd.
K242717Laboratorios Biogalenic Sterile Water for Inhalation, USPLaboratorios Biogalenic S.A. DE C.V.
K241778Hudson RCI Comfort Flo® CubCannula™Medline Industries, LP
K240163Hudson RCI® Comfort Flo Nasal Cannula; Hudson RCI® Comfort Flo Plus CannulaMedline Industries, LP
K234058F&P Optiflow Filtered Nasal Interface with Anesthesia Mask Compatibility (AA041J)Fisher & Paykel Healthcare, Ltd.

How long does FDA review take for BTT?

The median FDA review time for BTT is 98 days, measured across the 221 most recent decisions with both a received date and a decision date.

Review time here is decision date minus date received, as published by FDA. It is elapsed calendar time, not FDA review days — the two differ whenever the agency stops the clock for an additional information request.

Source: openFDA device/510k · retrieved

Are there recalls in BTT?

openFDA lists 69 recall records against product code BTT. A recall record covers one firm's corrective action and may span many device lots.

  • Z-0158-2026Open, ClassifiedFisher & Paykel Healthcare, Ltd.

    When unintentionally disconnected from power source, humidifier device (used to deliver high flow warmed and humidified respiratory gases) may sound audible alert for less than 120 seconds, which may delay user awareness to reconnect power, which could lead to oxygen desaturation, hypoxia. Disinfection kit user manual updated to include checking the audible alert prior to use on a new patient.

  • Z-1823-2024Open, ClassifiedFisher & Paykel Healthcare, Ltd.

    Humidifier devices, used to deliver high flow respiratory therapy to patients, manufactured before 14 August 2017, have a speaker configuration that may result in distorted, intermittent or inaudible alarm sound levels. In the absence of an audible alarm, if there is an interruption to therapy, a patient may experience oxygen desaturation.

  • Z-1272-2023Open, ClassifiedVapotherm, Inc.

    There have been reports of excessive condensation associated with certain lots of the Low Flow Disposable Patient Circuits (DPCs) used with Precision Flow System which may lead to excessive rainout.

  • Z-1385-2022CompletedHamilton Medical AG

    When starting a humidifier, intended for respiratory gas conditioning during invasive and noninvasive mechanical ventilation, with an empty chamber, and water is not filled into the chamber, the low water level alarm will be delayed and medical staff are unaware that there is no water in the chamber.

  • Z-1112-2020TerminatedTeleflex Medical

    There is the potential for water to flood the column and enter the circuit under circumstances where an abnormal pressure differential is created between the water bottle and the column during high flow oxygen therapy.

Showing the 5 most recently initiated of 69. Recall class comes from openFDA's enforcement endpoint, which does not carry every recall — where it is missing, none is shown rather than guessed. Status is FDA's own wording; a terminated recall is a closed one, and the total spans the code's whole history, not just what is open today.

Source: openFDA device/recall · retrieved

How many adverse events are reported for BTT?

MAUDE holds 3,805 adverse-event reports naming product code BTT, 2,351 of them received in the last 12 months.

MAUDE reports are submitted by manufacturers, importers, user facilities and the public. They are unverified, and a report is not proof that the device caused the event.

Source: openFDA device/event · retrieved

Is adverse-event reporting in BTT unusual?

4 months sit above BTT's own expected range: 1 February 2025, 1 April 2025, 1 October 2025, 1 November 2025.

Monthly adverse-event reports naming BTT, against the expected range computed from this code's own history. Shaded band is the expected range; a bar above it is the month flagged. Retrieved 11 August 2026.
Reports received per month for BTT, with the expected range and whether the month fell outside it.
MonthReportsExpectedVerdict
38Insufficient historyNo expected range — too little history
63Insufficient historyNo expected range — too little history
86Insufficient historyNo expected range — too little history
48Insufficient historyNo expected range — too little history
55Insufficient historyNo expected range — too little history
68Insufficient historyNo expected range — too little history
55Insufficient historyNo expected range — too little history
62Insufficient historyNo expected range — too little history
37Insufficient historyNo expected range — too little history
32Insufficient historyNo expected range — too little history
48Insufficient historyNo expected range — too little history
41Insufficient historyNo expected range — too little history
35Insufficient historyNo expected range — too little history
42Insufficient historyNo expected range — too little history
41Insufficient historyNo expected range — too little history
49Insufficient historyNo expected range — too little history
37Insufficient historyNo expected range — too little history
35Insufficient historyNo expected range — too little history
50Insufficient historyNo expected range — too little history
40Insufficient historyNo expected range — too little history
51Insufficient historyNo expected range — too little history
4229–51Within expected (29–51)
4827–44Above expected (27–44)
4532–56Within expected (32–56)
6933–59Above expected (33–59)
6531–68Within expected (31–68)
6333–80Within expected (33–80)
6552–132Within expected (52–132)
6833–93Within expected (33–93)
8538–98Within expected (38–98)
22343–102Above expected (43–102)
48121–192Above expected (21–192)
4830–519Within expected (0–519)
3890–758Within expected (0–758)
2900–656Within expected (0–656)
3510–709Within expected (0–709)

21 months do not have a full, unbroken year of history before them, so no expected range is shown for those. Insufficient history is reported as insufficient rather than as zero: an empty baseline would turn a gap in our data into a spike. Method: ewma_alpha_0.3_sd_2 corpus_adjusted. Counts are divided by the corpus-wide volume for that month before comparison, so a rise across all of MAUDE is not reported as a rise in BTT.

What are the predicate devices in BTT?

FDA publishes no machine-readable predicate field, so no predicate chain is recorded for this code yet.

A predicate chain matters because a device inherits the safety history of what it was compared to. FDA publishes the chain only inside each 510(k) summary PDF, never as data — so where we have edges, they are read from those documents, and where we do not, we say so instead of showing an empty list.

Who files 510(k)s in BTT?

Across the 221 most recent decisions, these applicants filed most often in BTT.

Most frequent applicants in BTT among recent decisions.
ApplicantRecent clearances
Fisher & Paykel Healthcare, Ltd.25
Fisher & Paykel Allied Products , Ltd.11
Vapotherm, Inc.10
Travenol Laboratories, S.A.9
Respiratory Care, Inc.8

Applicant names above are exactly as FDA published them, so one company can appear under several spellings.

The same makers, after name resolution

One company in BTT files under more than one spelling. Resolving them to one identity — across all six datasets, not just this one — is what makes a joined count possible at all.

Companies in BTT whose FDA filings use more than one spelling of the same name.
CompanyClearancesFDA spellings merged
Fisher & Paykel Healthcare, Ltd.282

Merges are measured against a hand-labelled sample and held above 98% precision; pairs the matcher is unsure of are queued for a person rather than merged. See DeviceSignal.

Source: openFDA device/510k · retrieved

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Data on this page comes from FDA's public openFDA API and is US public domain (CC0). DeviceSignal is an independent commercial service and is not affiliated with the U.S. Food and Drug Administration. Information only, not regulatory advice. Verify anything you rely on against open.fda.gov.